Pharmacological Properties of DOV 315,090, an ocinaplon metabolite
نویسندگان
چکیده
منابع مشابه
Pharmacological Properties of DOV 315,090, an ocinaplon metabolite
BACKGROUND Compounds targeting the benzodiazepine binding site of the GABAA-R are widely prescribed for the treatment of anxiety disorders, epilepsy, and insomnia as well as for pre-anesthetic sedation and muscle relaxation. It has been hypothesized that these various pharmacological effects are mediated by different GABAA-R subtypes. If this hypothesis is correct, then it may be possible to de...
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Rhus coriaria L. is known as Sumac. R. coriaria extracts are important in drug development with numerous pharmacological reputations in the South-Eastern Anatolia, Mediterranean area and Western Asia especially in Iran. Regarding the new multi-functional properties of R. coriaria and the related valuable ongoing reports, we were prompted to review the phytochemical an...
متن کاملDov Sagi
Dov Sagi was born in Nahariya, a coastal town in northern Israel. He studied at the Hebrew University of Jerusalem, where he received a BSc in Physics and Mathematics and a PhD in Neurobiology (1982). He then spent two years at AT&T Bell Laboratories, followed by a brief period at Caltech, as a post-doc with Bela Julesz. In 1985 he joined the Weizmann Institute of Science where he currently hol...
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Irinotecan, or CPT-11 (7-ethyl-10-[4-(1-piperidino)-1-piperidino]carbonyloxycamptothecine++ +), is a water-soluble derivative of camptothecine with promising activity against several types of malignancies. In addition to 7-ethyl-10-hydroxycamptothecine (SN-38), its active metabolite, we were able to identify several metabolites in the plasma of patients treated with this drug, especially an oxi...
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در این پایان نامه، درهمتنیدگی بین یک سیستم نقطه کوانتومی دوگانه(مولکول نقطه کوانتومی) و میدان مورد مطالعه قرار گرفته است. از آنتروپی ون نیومن به عنوان ابزاری برای بررسی درهمتنیدگی بین اتم و میدان استفاده شده و تاثیر پارامترهای مختلف، نظیر تونل زنی(که توسط تغییر ولتاژ ایجاد می شود)، شدت میدان و نسبت دو گسیل خودبخودی بر رفتار درجه درهمتنیدگی سیستم بررسی شده اشت.با تغییر هر یک از این پارامترها، در...
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ژورنال
عنوان ژورنال: BMC Pharmacology
سال: 2008
ISSN: 1471-2210
DOI: 10.1186/1471-2210-8-11